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Sexual Health Melanocortin receptor agonist

Melanotan II

Also known as: MT-2 · MT-II · Melanotan 2

A synthetic analog of the melanocyte-stimulating hormone that is most associated with discussion around skin tanning and, through its melanocortin activity, libido and sexual arousal.

Class

Melanocortin receptor agonist

Default unit

mg

Common route

Subcutaneous

Typical half-life

~30–60 min

Frequency

Varies by use

Commonly associated areas

Illustrative map of the body systems Melanotan II is most often discussed in relation to. Relative emphasis only — not a measure of efficacy or a medical claim.

Libido / arousal 80
Skin pigmentation (tanning) 88
Appetite influence 50
Mood / motivation 40
Recovery 30

Proposed mechanisms / pathways

Melanocortin receptor agonism (MC1R, MC4R) α-MSH analog Melanin synthesis stimulation

What is Melanotan II?

Melanotan II is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH), a naturally occurring peptide in the melanocortin system. It is most associated with skin tanning, because it stimulates the production of melanin, and is also widely discussed for its effects on libido and sexual arousal through its broader melanocortin activity. It is a research chemical, not an approved general-use medicine.

How it is thought to work

Melanotan II is thought to act as a non-selective melanocortin receptor agonist, binding receptors including MC1R and MC4R. Activity at MC1R is associated with stimulating melanin synthesis in skin cells, which is linked to its tanning reputation, while activity at MC4R in the central nervous system is associated with the libido and arousal effects it is often discussed for. It is also reported to influence appetite. These mechanisms are described as tentative and much of the discussion draws on early or limited research rather than settled human data.

Educational only — not medical advice

This page is educational and is not a recommendation, dose, or medical claim. Melanotan II is a research chemical that is not approved as a general-use medicine — nothing here suggests how it should be used. Consult a qualified healthcare provider and follow the laws in your area.

Tracking Melanotan II in LynkDose

Because Melanotan II is associated with effects on both pigmentation and arousal, the useful thing to track is how those subjective signals change over time. In LynkDose, log the dose and time of each injection, then add notes on libido, skin tone, and appetite. The value of tracking is watching how these responses build and settle across a full cycle rather than judging from any single day.

Commonly discussed for

  • Interest in skin tanning via melanin stimulation
  • Libido and sexual-arousal effects through melanocortin pathways
  • General exploration of melanocortin-system effects

Often stacked: Generally explored on its own; the related compound PT-141 is sometimes discussed for sexual-arousal interest without the pigmentation effect.

How to track Melanotan II in LynkDose

Melanotan II’s effects span both pigmentation and arousal, so log the dose and time alongside subjective notes on libido and any skin changes, then watch how those signals shift over a cycle.

Deeper read: How to Track a Peptide Cycle: A Complete Guide

Not medical advice

This page is educational and does not recommend, prescribe, or dose any compound. Many peptides are research chemicals not approved for general human use. Always consult a qualified healthcare provider and follow the laws in your area.

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