LL-37
Also known as: Cathelicidin · CAP-18 fragment
LL-37 is the only human cathelicidin-derived antimicrobial peptide, most associated with innate immune defense and inflammation modulation.
Class
Antimicrobial host-defense peptide
Default unit
mg
Common route
Subcutaneous
Typical half-life
Not well established
Frequency
Varies by use
Commonly associated areas
Illustrative map of the body systems LL-37 is most often discussed in relation to. Relative emphasis only — not a measure of efficacy or a medical claim.
Proposed mechanisms / pathways
What is LL-37?
LL-37 is the only known human cathelicidin-derived antimicrobial peptide, formed when the precursor protein hCAP-18 is cleaved to release a 37-amino-acid active fragment that begins with two leucine residues — the source of its name. It is a naturally occurring part of the body’s innate immune system, found in immune cells, skin, and mucosal surfaces, and in the peptide community it is discussed in the context of immune defense and inflammation modulation.
How it is thought to work
LL-37 is thought to act on two broad fronts. It is reported to directly disrupt the membranes of certain bacteria and other microbes, and it is also described as an immune-signaling molecule that can influence the recruitment and behavior of immune cells and shape inflammatory responses. Much of what is known comes from laboratory and preclinical work, and its effects appear highly context-dependent, so these mechanisms should be read as general and provisional rather than settled.
Educational only — not medical advice
LL-37 is a research peptide and is not an approved medication for general human use. Nothing here is a recommendation, dose, or medical claim. Consult a qualified healthcare provider and follow the laws in your area.
Tracking LL-37 in LynkDose
Because LL-37 is explored for very different reasons, LynkDose is most useful when you record your intended purpose with each entry along with any tolerability and injection-site observations. Logging dates and how you felt over time lets you separate genuine patterns from noise and keep a clear, honest record you can revisit later.
Commonly discussed for
- Innate immune support
- Inflammation modulation
- Skin and barrier-tissue contexts
How to track LL-37 in LynkDose
Because LL-37 is used in widely varying contexts, the most useful thing to log is your intended purpose alongside each entry, plus any tolerability or skin/injection-site notes, so observations stay tied to what you were actually doing.
Deeper read: How to Track a Peptide Cycle: A Complete Guide
Not medical advice
This page is educational and does not recommend, prescribe, or dose any compound. Many peptides are research chemicals not approved for general human use. Always consult a qualified healthcare provider and follow the laws in your area.